High Quality Proteins Supplier
With over 20 years of experience in peptide synthesis, we have advanced peptide synthesis instruments, professional team, and extensive expertise in peptide synthesis and purification processes. Our advanced peptide synthesis platform and quality control system work together to provide clients with high-quality products.
In peptide synthesis, when a peptide is reported as being 95% pure, it means that 95% of the material in the sample consists of the desired peptide sequence. The remaining 5% is composed of impurities or related substances. These impurities can arise from various sources during the synthesis, purification, and handling processes. Common impurities in peptide synthesis include:
Incomplete Coupling Products: These are peptides where not all amino acids have successfully coupled together during the synthesis, leading to shorter-than-desired sequences.
Deletion Sequences: These are peptides where one or more amino acids are missing in the sequence due to incomplete reactions during the synthesis.
Side-Chain Protecting Group Adducts: The protecting groups used during the synthesis may not be completely removed, leading to adducts with the peptide.
By-Products of Coupling Reactions: Some reactions may produce unwanted by-products that can contribute to impurities in the final product.
Residual Reagents: Traces of reagents used in the synthesis or purification steps may remain in the final product.
Analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) are commonly employed to assess the purity of synthesized peptides and identify the nature of impurities present. These techniques allow researchers to characterize the composition of the peptide sample and make adjustments to the synthesis or purification process if necessary.
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